1. Higher levels of sensitivity among direct collection methods
30% more sensitive than next closest competitor
Reduces false negatives by >33%
Limit of detection for PCR DIRECT Saliva Extraction Reagent was established using heat-inactivated SARS-CoV-2 (BEI) spiked into raw saliva. 5 µl of PCR DIRECT Saliva Extraction Reagent was added to the RT-PCR reaction (Taqman® Fast Virus 1-Step Master Mix). Data for non-Arcis methods is in public domain and taken from IFUs, EUAs or other manufacturer produced studies.
2. One-pipette protocol saves time and costs of isolation kits and consumables.
1. Collect Saliva
2. Add ARCIS Reagent
3. Direct to PCR
3. Use Automation by liquifying saliva without heat or beads
Improved saliva pipetting accuracy
The volume transferred was measured relative to the target volume. Results are averages of 32 replicates for saliva mixed with Arcis reagent and 8 replicates for raw saliva.
4. Hazard-free chemistry increases safety at reduced cost
Guanidine thiocyanate free
Compatible with bleach and acid-based cleaning procedures such as Hologic’s.
Eliminates exposure to injury from caustic chemicals
Avoids hazardous waste disposal costs.
Use PCR DIRECT Saliva Extraction Reagent to liquify saliva, lyse virus, extract RNA for direct RT-qPCR testing in 1 minute to achieve:
Greater sensitivity reduces false negatives > 30%
Automated liquid handling of saliva
Save time, avoid costs of kits, consumables and hazardous waste disposal